Tep22, a novel testicular expressed gene, is involved in the biogenesis of the acrosome and the midpiece of the sperm tail.

@article{Neesen2002Tep22AN,
  title={Tep22, a novel testicular expressed gene, is involved in the biogenesis of the acrosome and the midpiece of the sperm tail.},
  author={Juergen Neesen and Tobias Hartwich and Gunnar Brandhorst and Gerhard Aum{\"u}ller and Birgitta Glaeser and Peter Burfeind and Irene Mendoza-Lujambio},
  journal={Biochemical and biophysical research communications},
  year={2002},
  volume={297 4},
  pages={737-48}
}
To identify new genes that could be involved in the differentiation and function of male germ cells, we have screened a murine testis cDNA library and isolated a clone that was named Tep22. The gene encoding Tep22 consists of three exons and is localized in the telomeric region of mouse chromosome 12. Expression analyses with RNA from different adult tissues revealed that Tep22 is predominantly expressed in spermatocytes and spermatids of the murine testis. Four Tep22 transcript sizes ranging… CONTINUE READING

Similar Papers

Loading similar papers…