Tension, microtubule rearrangements, and the proper distribution of chromosomes in mitosis

@article{Ault1989TensionMR,
  title={Tension, microtubule rearrangements, and the proper distribution of chromosomes in mitosis},
  author={Jeffrey G. Ault and R. Bruce Nicklas},
  journal={Chromosoma},
  year={1989},
  volume={98},
  pages={33-39}
}
The basis for stable versus unstable kinetochore orientation was investigated by a correlated living-cell/ultrastructural study of grasshopper spermatocytes. Mal-oriented bivalents having both kinetochores oriented to one spindle pole were induced by micromanipulation. Such malorientations are stable while the bivalent is subject to tension applied by micromanipulation but unstable after tension is released. Unstable bivalents always reorient with movement of one kinetochore toward the opposite… CONTINUE READING
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