Tensin2 variant 3 is associated with aggressive tumor behavior in human hepatocellular carcinoma.

@article{Yam2006Tensin2V3,
  title={Tensin2 variant 3 is associated with aggressive tumor behavior in human hepatocellular carcinoma.},
  author={Judy Wai Ping Yam and Frankie Chi Fat Ko and Chung-Yiu Chan and Tai-On Yau and Edmund Kwok Kwan Tung and Thomas Ho-Yin Leung and Dong-Yan Jin and Irene Oi-Lin Ng},
  journal={Hepatology},
  year={2006},
  volume={44 4},
  pages={
          881-90
        }
}
Tensins are a new family of proteins that act as an important link among extracellular matrix, actin cytoskeleton, and signal transduction and have been implicated in human cancers. Tensin2 was initially identified in a search for new tensin family members that share extensive sequence homology with tensin1. Tensin2 was highly expressed in liver tissues. A recent study reported that one of the splicing variants of tensin2, variant 3, promotes cell migration. In the present study, we aimed to… CONTINUE READING

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Interaction of DISC1 with the PTB domain of Tensin2

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  • 2012
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