Tensin can induce JNK and p38 activation.

  title={Tensin can induce JNK and p38 activation.},
  author={B Z Katz and Muriel Zohar and Hidemi Teramoto and Kazuya Matsumoto and J. Silvio Gutkind and Diane C. Lin and Shanyan Lin and Kenneth M Yamada},
  journal={Biochemical and biophysical research communications},
  volume={272 3},
Cells organize diverse types of specialized adhesion sites upon attachment to extracellular matrix (ECM) components. One of the physiological roles of such cell-ECM interactions is to initiate and regulate adhesion-mediated signal transduction responses. The association of cells with fibronectin fibrils has been shown to regulate the JNK and p38 signaling pathways. We tested whether tensin, a cytoskeletal component localized to both focal contacts and fibronectin-associated fibrillar adhesions… CONTINUE READING