Tensile properties in collagen-rich tissues of Quarter Horses with hereditary equine regional dermal asthenia (HERDA).

@article{Bowser2014TensilePI,
  title={Tensile properties in collagen-rich tissues of Quarter Horses with hereditary equine regional dermal asthenia (HERDA).},
  author={Jacquelyn E Bowser and Steven H. Elder and Marzia Pasquali and Jesse G Grady and Ann M. Rashmir-Raven and R C Wills and Cyprianna E. Swiderski},
  journal={Equine veterinary journal},
  year={2014},
  volume={46 2},
  pages={216-22}
}
REASONS FOR PERFORMING STUDY Hereditary equine regional dermal asthenia (HERDA) is an autosomal recessive disorder of Quarter Horses characterised by skin fragility. Horses with HERDA have a missense mutation in peptidyl-prolyl cis-trans isomerase B (PPIB), which encodes cyclophilin B and alters folding and post translational modifications of fibrillar collagen. OBJECTIVES The study aimed to test the hypothesis that tendons, ligaments and great vessels, which, like skin, are rich in fibrillar… CONTINUE READING
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