Tenofovir to Prevent Hepatitis B Transmission in Mothers with High Viral Load.

Abstract

BACKGROUND Few data are available regarding the use of tenofovir disoproxil fumarate (TDF) during pregnancy for the prevention of mother-to-child transmission of hepatitis B virus (HBV). METHODS In this trial, we included 200 mothers who were positive for hepatitis B e antigen (HBeAg) and who had an HBV DNA level higher than 200,000 IU per milliliter… (More)
DOI: 10.1056/NEJMoa1508660

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