Tenofovir nephrotoxicity: acute tubular necrosis with distinctive clinical, pathological, and mitochondrial abnormalities.

@article{Herlitz2010TenofovirNA,
  title={Tenofovir nephrotoxicity: acute tubular necrosis with distinctive clinical, pathological, and mitochondrial abnormalities.},
  author={Leal C. Herlitz and Michael B Stokes and Jai Radhakrishnan and Vivette D D'agati and Glen S. Markowitz},
  journal={Kidney international},
  year={2010},
  volume={78 11},
  pages={
          1171-7
        }
}
Tenofovir, a widely prescribed antiretroviral medication for treatment of HIV-1 infection, is infrequently associated with renal dysfunction and biopsy findings of acute tubular necrosis. We examined the clinical and pathological findings in 13 cases of tenofovir nephrotoxicity (7 men and 6 women, mean age of 51.1±9.6 years). Patients received tenofovir therapy for a mean of 19.6 months (range, 3 weeks to 8 years; median 8 months). Nine patients presented with acute kidney injury, and four had… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 21 REFERENCES

41-year-old HIV patient with proteinuria and progressive renal dysfunction

  • R Agarwala, S Mohan, L Herlitz
  • Kidney Int
  • 2010

563–573

  • Harris M Perazella M. The nephrotoxic effects of HAART. N Izzedine H
  • Kidney International
  • 2010

Viread (Tenofovir Disoproxill Fumarate): Highlights of Prescribing Information

  • Gilead Sciences
  • Gilead Sciences: Foster City, CA,
  • 2010
1 Excerpt

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