Teniposide induces nuclear but not mitochondrial DNA degradation.

Teniposide [4'-demethylepipophyllotoxin-4-(4,6-O-thenylidene-beta-D- glucopyranoside) (VM-26)] is a cancer chemotherapeutic drug with a high target specificity for DNA topoisomerase II. This agent induces repairable protein-bridged double-strand DNA breaks, which have been correlated with cytotoxicity, but high concentrations of VM-26 also induce… (More)

6 Figures & Tables

Topics

Statistics

0204060'96'98'00'02'04'06'08'10'12'14'16'18
Citations per Year

83 Citations

Semantic Scholar estimates that this publication has 83 citations based on the available data.

See our FAQ for additional information.