Tenascins in stem cell niches.

  title={Tenascins in stem cell niches.},
  author={Ruth Chiquet-Ehrismann and Gertraud Orend and Matthias Chiquet and Richard P Tucker and Kim S. Midwood},
  journal={Matrix biology : journal of the International Society for Matrix Biology},
Tenascins are extracellular matrix proteins with distinct spatial and temporal expression during development, tissue homeostasis and disease. Based on their expression patterns and knockout phenotypes an important role of tenascins in tissue formation, cell adhesion modulation, regulation of proliferation and differentiation has been demonstrated. All of these features are of importance in stem cell niches where a precise regulation of growth versus differentiation has to be guaranteed. In this… CONTINUE READING
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