Tenascin Mr 220,000 isoform expression correlates with corneal cell migration.

@article{Kaplony1991TenascinM2,
  title={Tenascin Mr 220,000 isoform expression correlates with corneal cell migration.},
  author={A Kaplony and Dieter Robert Zimmermann and Ren{\'e} W. Fischer and Beat Albert Imhof and Bernhard F Odermatt and Kaspar H. Winterhalter and Lloyd D. Vaughan},
  journal={Development},
  year={1991},
  volume={112 2},
  pages={
          605-14
        }
}
The three isoforms of chicken tenascin, an extracellular matrix glycoprotein, are generated by alternatively spliced fibronectin type III domains. The resulting proteins migrate as bands of Mr 220,000 (ten220), Mr 200,000 (ten200) and Mr 190,000 (ten190) on SDS-PAGE. We describe here two monoclonal antibodies, one specific for ten220 (mAb T17) and another that recognizes all isoforms (mAb T16). These were used to examine the differential expression of isoforms during development. Most… CONTINUE READING

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