Tenascin-C is expressed by human glioma in vivo and shows a strong association with tumor blood vessels

Abstract

The extracellular matrix (ECM) protein tenascin-C (TN-C) is upregulated within glioma tissues and cultured glioma cell lines. TN-C possesses a multi-modular structure and a variety of functional properties have been reported for its domains. We describe five novel monoclonal antibodies identifying different domains of TN-C. The epitopes for these antibodies… (More)
DOI: 10.1007/s00441-013-1704-9

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