Tenascin-C expression in prostatic intraepithelial neoplasia (PIN): a marker of progression?

@article{Xue1998TenascinCEI,
  title={Tenascin-C expression in prostatic intraepithelial neoplasia (PIN): a marker of progression?},
  author={Yi Chuan Xue and Frank M M Smedts and Mieke A. H. E. Latijnhouwers and E. T. G. Ruijter and Tilly Wilhelmina Aalders and Jean J. M. C. H. de la Rosette and Frans M. J. Debruyne and Jack A Schalken},
  journal={Anticancer research},
  year={1998},
  volume={18 4A},
  pages={2679-84}
}
BACKGROUND Tenascin (tenascin-C) has been suggested to be associated with active epithelial-stromal interactions. We evaluated tenascin expression in tissue remodelling processes presumably associated with PIN and prostate carcinoma (PCa). MATERIALS AND METHODS Tenascin immunoreactivity was evaluated in 38 PIN lesions (low-grade = 5, high-grade = 33) from 27 paraffin-embedded PCa specimens, and compared with expression in pre-existent (normal) prostate, benign prostatic hyperplasia (BPH), and… CONTINUE READING

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