Tenascin-C: Form versus function

  title={Tenascin-C: Form versus function},
  author={Sean P Giblin and Kim S. Midwood},
  booktitle={Cell adhesion & migration},
Tenascin-C is a large, multimodular, extracellular matrix glycoprotein that exhibits a very restricted pattern of expression but an enormously diverse range of functions. Here, we discuss the importance of deciphering the expression pattern of, and effects mediated by, different forms of this molecule in order to fully understand tenascin-C biology. We focus on both post transcriptional and post translational events such as splicing, glycosylation, assembly into a 3D matrix and proteolytic… CONTINUE READING