Tenascin: an extracellular matrix protein involved in tissue interactions during fetal development and oncogenesis.

@article{ChiquetEhrismann1986TenascinAE,
  title={Tenascin: an extracellular matrix protein involved in tissue interactions during fetal development and oncogenesis.},
  author={Ruth Chiquet-Ehrismann and Eleanor J Mackie and Celeste A Pearson and Teruyo Sakakura},
  journal={Cell},
  year={1986},
  volume={47 1},
  pages={131-9}
}
The extracellular matrix protein tenascin (previously described as myotendinous antigen) is selectively present in the mesenchyme surrounding fetal rat mammary glands, hair follicles, and teeth, three organ anlagen where the mesenchyme is essential for development. No tenascin is detectable in the normal adult mammary gland. Carcinogen-induced mammary tumors contained tenascin in their fibrous tissue. As reported for the molecule described as a "hexabrachion," tenascin contaminates so-called… CONTINUE READING
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