Ten_m3 Regulates Eye-Specific Patterning in the Mammalian Visual Pathway and Is Required for Binocular Vision

@article{Leamey2007Ten_m3RE,
  title={Ten_m3 Regulates Eye-Specific Patterning in the Mammalian Visual Pathway and Is Required for Binocular Vision },
  author={Catherine A. Leamey and Sam Merlin and Paul Lattouf and Atomu Sawatari and Xiaohong Zhou and Natasha Demel and Kelly A. Glendining and Toshitaka Oohashi and Mriganka Sur and Reinhard F{\"a}ssler},
  journal={PLoS Biology},
  year={2007},
  volume={5},
  pages={577 - 589}
}
Binocular vision requires an exquisite matching of projections from each eye to form a cohesive representation of the visual world. Eye-specific inputs are anatomically segregated, but in register in the visual thalamus, and overlap within the binocular region of primary visual cortex. Here, we show that the transmembrane protein Ten_m3 regulates the alignment of ipsilateral and contralateral projections. It is expressed in a gradient in the developing visual pathway, which is consistently… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 57 references

Origins of crossed and uncrossed retinal projections in pigmented and albino mice.

The Journal of comparative neurology • 1980
View 5 Excerpts
Highly Influenced

Chemoaffinity in the Orderly Growth of Nerve Fiber Patterns and Connections.

Proceedings of the National Academy of Sciences of the United States of America • 1963
View 4 Excerpts
Highly Influenced

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