Ten years of rizatriptan: from development to clinical science and future directions.

@article{Hargreaves2009TenYO,
  title={Ten years of rizatriptan: from development to clinical science and future directions.},
  author={Richard J. Hargreaves and Chris R Lines and Alan Mark Rapoport and Tony W. Ho and Fred D. Sheftell},
  journal={Headache},
  year={2009},
  volume={49 Suppl 1},
  pages={S3-20}
}
The year 2008 marked the 10th anniversary since rizatriptan was first launched for the acute treatment of migraine. In this article we discuss the concepts that motivated the preclinical and clinical development of rizatriptan, the clinical evidence that has driven its use over the past decade, rizatriptan's overall contribution to the field, and future… CONTINUE READING