Ten-year trends in prevalence of Down syndrome in a developing country: impact of the maternal age and prenatal screening.

OBJECTIVE This study examines trends in total and live birth prevalence of trisomy 21 (T21) with regard to increasing maternal age and the introduction of prenatal diagnosis in Bosnia and Herzegovina. METHOD The prenatal detection was introduced in January 2008 in 3 hospitals and assessed until December 31, 2015. In this study, 99 fetuses and 330 babies… CONTINUE READING