Ten-year results of a randomized trial comparing a conservative treatment to mastectomy in early breast cancer.

Abstract

A randomized trial was conducted at the Institut Gustave-Roussy (IGR) between 1972 and 1980 comparing tumorectomy and breast irradiation with modified radical mastectomy. One hundred and seventy-nine patients with an infiltrating breast carcinoma up to 20 mm in diameter at macroscopic examination were included: 88 had conservative management, and 91 a mastectomy. All patients had a low-axillary dissection with immediate histological examination. For the patients with positive axillary nodes, a complete axillary dissection was undertaken. Overall survival, distant metastasis, contralateral breast cancer and locoregional recurrence rates were not significantly different between the two treatment groups.

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@article{Sarrazin1989TenyearRO, title={Ten-year results of a randomized trial comparing a conservative treatment to mastectomy in early breast cancer.}, author={Danielle Sarrazin and Monique G. L{\^e} and Rodrigo A Arriagada and Gen{\`e}vieve Contesso and Florence Fontaine and M L Spielmann and France Rochard and Thierry Le Chevalier and J Lacour}, journal={Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology}, year={1989}, volume={14 3}, pages={177-84} }