Ten-year follow-up of antidiabetic drug use, nonadherence, and mortality in a defined population with type 2 diabetes mellitus.

@article{Brown1999TenyearFO,
  title={Ten-year follow-up of antidiabetic drug use, nonadherence, and mortality in a defined population with type 2 diabetes mellitus.},
  author={Jonathan Betz Brown and Gregory A Nichols and Harry S. Glauber and Alan W Bakst},
  journal={Clinical therapeutics},
  year={1999},
  volume={21 6},
  pages={1045-57}
}
Studies performed for drug registration provide little insight into the long-term use and effectiveness of drugs in "real world" populations and settings. To obtain such insight, we used 10 years of electronic medical-record data from Kaiser Permanente Northwest Division, a large, group-model health maintenance organization in the United States, to study drug transitions, lapses in drug therapy, and mortality among 693 persons with newly diagnosed type 2 diabetes mellitus in 1988. We also… CONTINUE READING

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