Ten ways in which He Jiankui violated ethics
@article{Krimsky2019TenWI, title={Ten ways in which He Jiankui violated ethics}, author={Sheldon Krimsky}, journal={Nature Biotechnology}, year={2019}, volume={37}, pages={19-20} }
1. Roskams-Edris, D., Anderson-Redick, S., Kiss, Z.H. & Illes, J. Nat. Biotechnol. 35, 119–121 (2017). 2. Foster, A.M. et al. US patent 9,327,069 (2006). 3. Wagner, T.A. et al. US patent 9,050,463 (2015). 4. Krueger, R. & Weiss, D. US patent 9,283,378 (2012). 5. Association for Molecular Pathology v. Myriad Genetics, Inc. 569 U.S. 576 (2013). 6. 35 U.S. Code §287(c). 7. United States Constitution, Article I, Section 8, Clause 8. 8. Bonito Boats, Inc. v. Thunder Craft Boats, Inc. 489 U.S. 141…
33 Citations
Governance of Emerging Biotechnologies: Lessons from Two Chinese Cases
- BiologyThe American journal of bioethics : AJOB
- 2022
A reflexive, anticipatory, and deliberative approach to unanticipated discoveries: Ethical lessons from IBlastoids, and a framework for responsible innovation.
CRISPR-Cas9 and He Jiankui's Case: an Islamic Bioethics Review using Maqasid al-Shari'a and Qawaid Fighiyyah.
- BiologyAsian bioethics review
- 2021
It is argued that from an Islamic standpoint, the therapeutic application of CRISPR-Cas9 for germline editing may be permissible if the safety and efficacy concerns are resolved and if the principles of Maqasid al-Shari'a are fulfilled.
Germline Genome Editing Research: What Are Gamete Donors (Not) Informed About in Consent Forms?
- BiologyThe CRISPR journal
- 2020
The analysis of informed consent forms for egg and sperm donation used in a widely publicized study where genome editing was used to correct a disease-causing genetic mutation in human embryos indicates deficiencies in how the forms addressed various issues.
Reexamining the Ethics of Human Germline Editing in the Wake of Scandal.
- MedicineMayo Clinic proceedings
- 2020
Getting serious about the challenge of regulating germline gene therapy
- MedicinePLoS biology
- 2019
The announcement of He Jiankui's germline editing of human embryos has been followed by a torrent of almost universal criticism of the claim on scientific and ethical grounds, but a serious, rigorous framework must be imposed that insures that such research is done following the highest ethical standards.
Ordo-Responsibility for Germline Gene Editing.
- Political ScienceThe CRISPR journal
- 2020
The basic structure of an appropriate rule-finding process is explained, a possible pathway toward an international framework is outlined, and minimal requirements that are needed are discussed that contribute to the debate on how to govern genome-editing technologies and GGE globally.
Contesting the Geneticization Thesis in Human Reproduction: Dealing with Spiral Shaped Processes and Technoscientific Imaginaries
- Medicine
- 2019
It is concluded that the regulation of reproductive genetics is becoming more critical and complex and a broad and inclusive societal debate may overcome the difficulty of drawing a clear line between medical uses and non-medical uses of genetic selection and engineering.
Realigning gene editing with clinical research ethics: What the “CRISPR Twins” debacle means for Chinese and international research ethics governance
- MedicineAccountability in research
- 2019
Commentary surrounding the question of the enforceability of Chinese regulations in the case of the "CRISPR babies" argues that Chinese regulations do align with internationally accepted standards.
Canada's Assisted Human Reproduction Act: Pragmatic Reforms in Support of Research
- Political ScienceFront. Med.
- 2019
It is argued that the current regulation of research using human reproductive materials is not proportionate, not responsive to the uncertain threats posed to human and environmental health and safety, and is not considerate of diverse values in a democratic society.
Regulating reproductive genetic services: dealing with spiral-shaped processes and techno-scientific imaginaries
- BiologyJournal of Assisted Reproduction and Genetics
- 2021
There is a ‘grey-zone’ of RGS regulations regarding four procedures: the use of germline genome modification (GGM) for severe monogenic disorders, preimplantation genetic testing (PGT) for detection of chromosomal abnormalities, PGT for multifactorial diseases, and PGT with whole-exome screening.
References
SHOWING 1-10 OF 11 REFERENCES
Disease Resistance and the Definition of Genetic Enhancement
- MedicineFront. Genet.
- 2017
An overview of the key ethical features of CCR5-Δ32 deletion is provided (including its frequency in various populations, biological mechanism, benefits for individuals, and use in previous clinical trials) to offer some potential guideposts for the continuing discussion on how to classify “enhancements” in the age of CRISPR gene editing.
Draft Ethical Principles for Therapeutic Assisted Reproductive Technologies
- Sociology
- 2018
The identification of a core set of fundamental human values to frame, guide, and restrict clinical applications that communities around the world can share and localize based on religious beliefs, culture, and public-health challenges is proposed.
Retracted: Draft Ethical Principles for Therapeutic Assisted Reproductive Technologies
- The CRISPR Journal
- 2018
Should we edit the human germline? Is consensus possible or even desirable?
- Hastings Center report
- 2018
Should we edit the human germline? Is consensus possible or even desirable? Hastings Center report
- https://www.thehastingscenter.org/edit-humangermline-consensus-possible-even-desirable
- 2018
the case of the first gene-edited babies
- The Conversation
- 2018
Rogue science strikes again : the case of the first gene - edited babies
Rogue science strikes again: the case of the first gene-edited babies. The Conversation