Ten-day Quadruple therapy comprising proton-pump inhibitor, bismuth, tetracycline, and levofloxacin achieves a high eradication rate for Helicobacter pylori infection after failure of sequential therapy.

@article{Hsu2014TendayQT,
  title={Ten-day Quadruple therapy comprising proton-pump inhibitor, bismuth, tetracycline, and levofloxacin achieves a high eradication rate for Helicobacter pylori infection after failure of sequential therapy.},
  author={Ping-I Hsu and Wen-chi Chen and Feng-Woei Tsay and Chih-An Shih and Sung-Shuo Kao and Huay-Min Wang and Hsien-Chung Yu and Kwok-Hung Lai and Hui-hwa Tseng and N. J. Peng and Angela Shin-Yih Chen and Chao-Hung Kuo and D T Wu},
  journal={Helicobacter},
  year={2014},
  volume={19 1},
  pages={74-9}
}
BACKGROUND Sequential therapy has been recommended in the Maastricht IV/Florence Consensus Report as the first-line treatment for Helicobacter pylori eradication in regions with high clarithromycin resistance. However, it fails in 5-24% of infected subjects, and the recommended levofloxacin-containing triple rescue therapy only achieves a 77% eradication rate after failure of sequential therapy. AIM To investigate the efficacy of a novel quadruple therapy comprising proton-pump inhibitor… CONTINUE READING
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