Temporary bone tissue ischemia in the hind limb of the rabbit

@article{PKleboM1986TemporaryBT,
  title={Temporary bone tissue ischemia in the hind limb of the rabbit},
  author={D. P.K{\"a}leboM. and Carolina Johansson and T. Albrektssont},
  journal={Archives of orthopaedic and traumatic surgery},
  year={1986},
  volume={105},
  pages={321-325}
}
With in situ bone vital microscopy it was demonstrated that a cuff pressure of 300 mm Hg applied over the rabbit thigh is sufficient to cause a complete vascular standstill in the tibial cortex. Cuff-induced tissue ischemia applied for 30 min did not result in any adverse bone tissue reactions over a follow-up period of 30 days. Locally applied isolated bone ischemia for 3 or 6 h resulted in an inflammatory response, and 4–6 weeks after the 6-h ischemia bone resorption was evident. Anhand einer… CONTINUE READING

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