Temporal variation of the merozoite surface protein-2 gene of Plasmodium falciparum.

@article{Eisen1998TemporalVO,
  title={Temporal variation of the merozoite surface protein-2 gene of Plasmodium falciparum.},
  author={Damon P. Eisen and Helen Billman-Jacobe and Victor Fray Marshall and David J. Fryauff and Ross L Coppel},
  journal={Infection and immunity},
  year={1998},
  volume={66 1},
  pages={239-46}
}
Extensive polymorphism of key parasite antigens is likely to hamper the effectiveness of subunit vaccines against Plasmodium falciparum infection. However, little is known about the extent of the antigenic repertoire of naturally circulating strains in different areas where malaria is endemic. To address this question, we conducted a study in which blood samples were collected from parasitemic individuals living within a small hamlet in Western Irian Jaya and subjected to PCR amplification… CONTINUE READING

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