Temporal trends of antimicrobial resistance and clonality of invasive Streptococcus pneumoniae isolates in Finland, 2002 to 2006.

@article{Siira2009TemporalTO,
  title={Temporal trends of antimicrobial resistance and clonality of invasive Streptococcus pneumoniae isolates in Finland, 2002 to 2006.},
  author={Lotta Siira and Merja Rantala and J. P. Jalava and Antti J. Hakanen and Pentti Huovinen and Tarja H Kaijalainen and Outi Lyytik{\"a}inen and Anni Virolainen},
  journal={Antimicrobial agents and chemotherapy},
  year={2009},
  volume={53 5},
  pages={2066-73}
}
The antimicrobial resistance of Streptococcus pneumoniae, or pneumococcus, is a growing global problem. In our study, 3,571 invasive pneumococcal isolates, recovered from blood and cerebrospinal fluid samples from patients in Finland between the years 2002 and 2006, showed an increase in erythromycin nonsusceptibility from 16% to 28% (P < 0.0001) over the 5-year study period, as well as a doubling of penicillin nonsusceptibility from 8% to 16% (P < 0.0001). Erythromycin nonsusceptibility… CONTINUE READING

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