Temporal renal expression of angiogenic growth factors and their receptors in experimental diabetes: role of the renin-angiotensin system.

@article{Rizkalla2005TemporalRE,
  title={Temporal renal expression of angiogenic growth factors and their receptors in experimental diabetes: role of the renin-angiotensin system.},
  author={Bishoy Rizkalla and Josephine M Forbes and Zemin Cao and Geoffrey Boner and Mark Cooper},
  journal={Journal of hypertension},
  year={2005},
  volume={23 1},
  pages={
          153-64
        }
}
OBJECTIVE It has been postulated that vascular endothelial growth factor (VEGF) plays a role in the progression of renal injury. However, the role of other angiogenic factors and their receptors, such as the angiopoietins and Tie2, and in particular their relation to renoprotective therapies, such as agents that interrupt the renin-angiotensin system, have not been studied in the context of diabetes-related renal injury. DESIGN AND METHODS Renal expression of VEGF, angiopoietin-1 (Ang-1… CONTINUE READING

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