Temporal relationships between hormonal and hemodynamic changes in early human pregnancy.

  title={Temporal relationships between hormonal and hemodynamic changes in early human pregnancy.},
  author={Arlene B. Chapman and William T. Abraham and Stacy Zamudio and Carolyn Coffin and Aicha Merouani and David Z. Young and Ann -Christin Johnson and Fritz Osorio and Caren Goldberg and Lorna Grindlay Moore and Thomas Dahms and Robert Schrier},
  journal={Kidney international},
  volume={54 6},
BACKGROUND The systemic hemodynamic profile of human pregnancy is characterized by a decrease in mean arterial pressure, a rise in cardiac output and plasma volume in association with an increase in renal plasma flow and glomerular filtration rate. The factors and the time course responsible for the initial hemodynamic changes seen in human pregnancy have not been completely documented. We hypothesize that systemic and renal hemodynamic changes occur early, prior to the presence of the fetal… CONTINUE READING
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