Temporal relationship between serum adipokines, biomarkers of bone and cartilage turnover, and cartilage volume loss in a population with clinical knee osteoarthritis.

@article{Berry2011TemporalRB,
  title={Temporal relationship between serum adipokines, biomarkers of bone and cartilage turnover, and cartilage volume loss in a population with clinical knee osteoarthritis.},
  author={Patricia A Berry and Simon Wyn Jones and Flavia Cicuttini and Anita E Wluka and Rose A. Maciewicz},
  journal={Arthritis and rheumatism},
  year={2011},
  volume={63 3},
  pages={700-7}
}
OBJECTIVE The association of obesity with both hand and knee osteoarthritis (OA) is suggestive of a link between dysfunctional metabolism and joint integrity. Given the role of adipokines in mediating bone and cartilage homeostasis, we undertook this study to examine the relationship between adipokines and bone and cartilage biomarkers in a population of subjects with OA, and to determine whether adipokine levels predicted 2-year cartilage integrity. METHODS One hundred seventeen subjects… CONTINUE READING
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