• Medicine
• Published in
  Clinical chemistry and…
  2009
• DOI:10.1515/CCLM.2009.337

Temporal profile and clinical significance of serum neuron-specific enolase and S100 in ischemic and hemorrhagic stroke

@inproceedings{Brea2009TemporalPA,
  title={Temporal profile and clinical significance of serum neuron-specific enolase and S100 in ischemic and hemorrhagic stroke},
  author={David Brea and Tom{\'a}s Sobrino and Miguel Blanco and Iv{\'a}n Cristobo and Raquel Rodr{\'i}guez-Gonz{\'a}lez and Manuel Rodr{\'i}guez-Y{\'a}{\~n}ez and Octavio Moldes and Jes{\'u}s Agulla and Rogelio Leira and Jos{\'e} Castillo},
  booktitle={Clinical chemistry and laboratory medicine},
  year={2009}
}

• David Brea, Tomás Sobrino, +7 authors José Castillo

Abstract Background: Neuron-specific enolase (NSE) and S100 protein are implicated in several brain injuries, including stroke. Our objective was to analyze the temporal profile and the clinical significance of NSE and S-100 in acute ischemic (IS) and intracerebral hemorrhage (ICH). Methods: We studied 224 patients with IS and 44 patients with ICH. Computerized tomography (CT) scans were performed to assess infarct volume. Stroke severity was evaluated using the National Institute of Health… CONTINUE READING

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