Temporal pattern of renin and aldosterone secretion in men: effects of sodium balance.

@article{Vieweg1992TemporalPO,
  title={Temporal pattern of renin and aldosterone secretion in men: effects of sodium balance.},
  author={Wolfgang Vieweg and Johannes D. Veldhuis and R. M. Carey},
  journal={The American journal of physiology},
  year={1992},
  volume={262 5 Pt 2},
  pages={F871-7}
}
To investigate the pulsatile nature of basal and stimulated renin and aldosterone secretion, we sampled blood for plasma renin activity (PRA) and plasma aldosterone concentration at 10-min intervals for 24 h in nine normal supine human male subjects after equilibration in high- and low-sodium balance states. We evaluated serial hormonal measures by a quantitative waveform-independent deconvolution technique designed to compute the number, amplitude, and mass of underlying secretory bursts and… CONTINUE READING