Temporal hypometabolism at the onset of cryptogenic temporal lobe epilepsy

  title={Temporal hypometabolism at the onset of cryptogenic temporal lobe epilepsy},
  author={Peter Matheja and Torsten Kuwert and Peter L{\"u}demann and Matthias Weckesser and Christoph Kellinghaus and Gerhard Robert Schuierer and Beate Diehl and E. Bernd Ringelstein and Otmar Schober},
  journal={European Journal of Nuclear Medicine},
Most patients with intractable temporal lobe epilepsy (TLE) exhibit temporal glucose hypometabolism. The reasons for the development of this abnormality are as yet unclear. The current notion is that an initial injury causes seizures, which in turn give rise to hypometabolism. The aim of this study was to assess whether temporal reductions in glucose metabolism in non-lesional TLE are the result of repeated seizures or whether hypometabolism represents an initial disturbance at the onset of… CONTINUE READING


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