Temporal control of glucocorticoid neurodynamics and its relevance for brain homeostasis, neuropathology and glucocorticoid-based therapeutics

@article{Kalafatakis2016TemporalCO,
  title={Temporal control of glucocorticoid neurodynamics and its relevance for brain homeostasis, neuropathology and glucocorticoid-based therapeutics},
  author={Konstantinos Kalafatakis and G M Russell and Apostolos Zarros and Stafford L Lightman},
  journal={Neuroscience & Biobehavioral Reviews},
  year={2016},
  volume={61},
  pages={12-25}
}
Glucocorticoids mediate plethora of actions throughout the human body. Within the brain, they modulate aspects of immune system and neuroinflammatory processes, interfere with cellular metabolism and viability, interact with systems of neurotransmission and regulate neural rhythms. The influence of glucocorticoids on memory and emotional behaviour is well known and there is increasing evidence for their involvement in many neuropsychiatric pathologies. These effects, which at times can be in… CONTINUE READING

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