Temporal comparison of recombination and synaptonemal complex formation during meiosis in S. cerevisiae

@article{Padmore1991TemporalCO,
  title={Temporal comparison of recombination and synaptonemal complex formation during meiosis in S. cerevisiae},
  author={Ruth Padmore and L Cao and Nancy Kleckner},
  journal={Cell},
  year={1991},
  volume={66},
  pages={1239-1256}
}
  • Ruth Padmore, L Cao, Nancy Kleckner
  • Published in Cell 1991
  • Medicine, Biology, Materials Science
  • In synchronous cultures of S. cerevisiae undergoing meiosis, an early event in the meiotic recombination pathway, site-specific double strand breaks (DSBs), occurs early in prophase, in some instances well before tripartite synaptonemal complex (SC) begins to form. This observation, together with previous results, supports the view that events involving DSBs are required for SC formation. We discuss the possibility that the mitotic pathway for recombinational repair of DSBs served as the… CONTINUE READING

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