Temporal characterisation of amphetamine‐induced dopamine release assessed with [11C]raclopride in anaesthetised rodents

@article{Houston2004TemporalCO,
  title={Temporal characterisation of amphetamine‐induced dopamine release assessed with [11C]raclopride in anaesthetised rodents},
  author={G. C. Houston and S. Hume and E. Hirani and J. Goggi and P. Grasby},
  journal={Synapse},
  year={2004},
  volume={51}
}
  • G. C. Houston, S. Hume, +2 authors P. Grasby
  • Published 2004
  • Chemistry, Medicine
  • Synapse
  • Competition between endogenous neurotransmitters and radiolabelled tracers, as measured by positron emission tomography (PET), may provide a measure of endogenous neurotransmitter flux in vivo. For example, carbon‐11 labelled raclopride has been effectively used to monitor dopamine release following pharmacological and behavioural manipulations. The current study describes a rodent model of amphetamine‐induced [11C]raclopride reduction, which allowed the characterisation of the dose–response… CONTINUE READING
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    References

    SHOWING 1-10 OF 41 REFERENCES
    Kinetic Modeling of [11C]Raclopride: Combined PET-Microdialysis Studies
    • C. Endres, B. Kolachana, +5 authors R. Carson
    • Chemistry, Medicine
    • Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
    • 1997
    • 182
    Imaging D2 Receptor Occupancy by Endogenous Dopamine in Humans
    • 260
    • PDF