Temporal changes of neocortical high-frequency oscillations in epilepsy.

  title={Temporal changes of neocortical high-frequency oscillations in epilepsy.},
  author={Allison Pearce and Drausin Wulsin and Justin A. Blanco and Abba M. Krieger and Brian Litt and William C. Stacey},
  journal={Journal of neurophysiology},
  volume={110 5},
High-frequency (100-500 Hz) oscillations (HFOs) recorded from intracranial electrodes are a potential biomarker for epileptogenic brain. HFOs are commonly categorized as ripples (100-250 Hz) or fast ripples (250-500 Hz), and a third class of mixed frequency events has also been identified. We hypothesize that temporal changes in HFOs may identify periods of increased the likelihood of seizure onset. HFOs (86,151) from five patients with neocortical epilepsy implanted with hybrid (micro + macro… CONTINUE READING