Temporal aspects of O-glycosylation of glycoprotein C from herpes simplex virus type-1.

@article{SerafiniCessi1989TemporalAO,
  title={Temporal aspects of O-glycosylation of glycoprotein C from herpes simplex virus type-1.},
  author={Franca Serafini-Cessi and Fabio Dall'Olio and Nadia Malagolini and Gabriella Campadelli-Fiume},
  journal={The Biochemical journal},
  year={1989},
  volume={262 2},
  pages={479-84}
}
Herpes simplex virus type-1 glycoprotein C (gC1) contains several O-linked oligosaccharides clustered near N-linked chains, and Pronase digestion produces glycopeptides carrying both oligosaccharide types. We have taken advantage of this fact to investigate the temporal relationship between the initiation of O-linked chains and the processing of N-linked oligosaccharides. gC1 was isolated from herpes-simplex-virus-infected BHK (baby-hamster kidney) cells after short labelling periods with [3H… CONTINUE READING