Temporal and spatial variation of the human microbiota during pregnancy.

  title={Temporal and spatial variation of the human microbiota during pregnancy.},
  author={Daniel B. DiGiulio and Benjamin J. Callahan and Paul J. McMurdie and Elizabeth K. Costello and Deirdre J. Lyell and Anna Robaczewska and Christine L. Sun and Daniela S Aliaga Goltsman and Ronald J Wong and Gary M Shaw and David K. Stevenson and Susan P. Holmes and David A. Relman},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={112 35},
Despite the critical role of the human microbiota in health, our understanding of microbiota compositional dynamics during and after pregnancy is incomplete. We conducted a case-control study of 49 pregnant women, 15 of whom delivered preterm. From 40 of these women, we analyzed bacterial taxonomic composition of 3,767 specimens collected prospectively and weekly during gestation and monthly after delivery from the vagina, distal gut, saliva, and tooth/gum. Linear mixed-effects modeling, medoid… CONTINUE READING
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Characterization of the vaginal microbiota of healthy Canadian women through the menstrual cycle

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  • Microbiome
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Diversity of the vaginal microbiome correlates with preterm birth

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