Temporal and spatial distribution of immunoreactive PER1 and PER2 proteins in the suprachiasmatic nucleus and peri-suprachiasmatic region of the diurnal grass rat (Arvicanthis niloticus).

@article{Ramanathan2006TemporalAS,
  title={Temporal and spatial distribution of immunoreactive PER1 and PER2 proteins in the suprachiasmatic nucleus and peri-suprachiasmatic region of the diurnal grass rat (Arvicanthis niloticus).},
  author={Chidambaram Ramanathan and Antonio A. Nunez and Gladys S. Mart{\'i}nez and Michael David Schwartz and Laura Smale},
  journal={Brain research},
  year={2006},
  volume={1073-1074},
  pages={348-58}
}
The suprachiasmatic nucleus (SCN) of the hypothalamus contains the primary circadian pacemaker in both diurnal and nocturnal mammals. The lower subparaventricular zone (LSPV) immediately dorsal to the SCN may also play an important role in the regulation of circadian rhythms. The SCN contains a multitude of oscillator cells that generate circadian rhythms through transcriptional/translational feedback loops involving a set of clock genes including per1 and per2. Little is known about the… CONTINUE READING

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