Temporal and regional differences in brain concentrations of lithium in rats

@article{Mukherjee1976TemporalAR,
  title={Temporal and regional differences in brain concentrations of lithium in rats},
  author={Bhashkar Mukherjee and Paul T. Bailey and Sachindra N. Pradhan},
  journal={Psychopharmacology},
  year={1976},
  volume={48},
  pages={119-121}
}
Lithium (Li) concentrations have been estimated in several peripheral tissues (serum, heart, kidney, liver and skeletal muscle) and different brain areas (cortex, caudate nucleus, hypothalamus, diencephalon, midbrain, pons-medulla and cerebellum) at different intervals (0.5 to 48 h) after administrations of 3 mEq/kg of lithium chloride (LiCl). The Li concentrations in the brain areas increased gradually, reaching their peak at 8 h; the hypothalamus showed the highest concentration measured… CONTINUE READING

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References

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Showing 1-9 of 9 references

The effect of prolonged lithium treatment on the synthesis rate and turnover of monoamines in brain regions of rats

  • J. M. Morrison, H. D. Pritchard, M. C. Braude, W. D'Aguanno
  • Europ . J . Pharmacol .
  • 1970

Lithium studies . 3 . Distribution between serum and tissues

  • M. Schou, J. O. Cole, J. Levine, J. R. Wittenborn, T. Segawa, M. Nakano
  • Acta pharmacol . ( Kbh . )
  • 1958

Distribution ofparenterally administered lithium in plasma , brain and muscle of rats

  • M. S. Ebadi, V. J. Simmons, M. J. Lacy Hendrickson, S. P.
  • Amer . J . Physiol .
  • 1950

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