Temporal Trends of Antimicrobial Resistance and Clonality of Invasive Streptococcus pneumoniae Isolates in Finland, 2002 to 2006

  title={Temporal Trends of Antimicrobial Resistance and Clonality of Invasive Streptococcus pneumoniae Isolates in Finland, 2002 to 2006},
  author={L. Siira and M. Rantala and J. Jalava and A. Hakanen and P. Huovinen and T. Kaijalainen and O. Lyytik{\"a}inen and A. Virolainen},
  journal={Antimicrobial Agents and Chemotherapy},
  pages={2066 - 2073}
  • L. Siira, M. Rantala, +5 authors A. Virolainen
  • Published 2009
  • Biology, Medicine
  • Antimicrobial Agents and Chemotherapy
  • ABSTRACT The antimicrobial resistance of Streptococcus pneumoniae, or pneumococcus, is a growing global problem. In our study, 3,571 invasive pneumococcal isolates, recovered from blood and cerebrospinal fluid samples from patients in Finland between the years 2002 and 2006, showed an increase in erythromycin nonsusceptibility from 16% to 28% (P < 0.0001) over the 5-year study period, as well as a doubling of penicillin nonsusceptibility from 8% to 16% (P < 0.0001). Erythromycin… CONTINUE READING
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