Temporal Synaptic Tagging by Ih Activation and Actin Involvement in Long-Term Facilitation and cAMP-Induced Synaptic Enhancement

@article{Beaumont2002TemporalST,
  title={Temporal Synaptic Tagging by Ih Activation and Actin Involvement in Long-Term Facilitation and cAMP-Induced Synaptic Enhancement},
  author={Vahri Beaumont and Ning Zhong and Robert C Froemke and Robin W. Ball and Robert S. Zucker},
  journal={Neuron},
  year={2002},
  volume={33},
  pages={601-613}
}
Presynaptic I(h) channels become activated during a tetanus through membrane hyperpolarization resulting from Na(+) accumulation and electrogenic Na(+)/K(+) exchange. I(h) activation is obligatory for inducing long-term facilitation (LTF), a long-lasting synaptic strengthening. cAMP-induced synaptic enhancement also requires I(h) activation, and both processes are sensitive to actin depolymerization. Other mechanisms are responsible for expression of the responses. Once initiated, continued… CONTINUE READING
40 Citations
45 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 40 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 45 references

Newvideomicroscopy

  • I. Spector, F. Braet, N. R. Shochet, M. R. Bubb
  • J . Cell Biol .
  • 1999
Highly Influential
1 Excerpt

Similar Papers

Loading similar papers…