Temporal Differences in MicroRNA Expression Patterns in Astrocytes and Neurons after Ischemic Injury

@inproceedings{Ziu2011TemporalDI,
  title={Temporal Differences in MicroRNA Expression Patterns in Astrocytes and Neurons after Ischemic Injury},
  author={Mateo Ziu and Lauren Fletcher and Shushan Rana and David F. Jimenez and Murat H Digicaylioglu},
  booktitle={PloS one},
  year={2011}
}
MicroRNAs (miRNAs) are small, non-protein-coding RNA molecules that modulate gene translation. Their expression is altered in many central nervous system (CNS) injuries suggesting a role in the cellular response to stress. Current studies in brain tissue have not yet described the cell-specific temporal miRNA expression patterns following ischemic injury. In this study, we analyzed the expression alterations of a set of miRNAs in neurons and astrocytes subjected to 60 minutes of ischemia and… CONTINUE READING