Temporal Characterization of Marburg Virus Angola Infection following Aerosol Challenge in Rhesus Macaques.

@article{Lin2015TemporalCO,
  title={Temporal Characterization of Marburg Virus Angola Infection following Aerosol Challenge in Rhesus Macaques.},
  author={Kenny L. Lin and Nancy A. Twenhafel and John H. Connor and Kathleen A. Cashman and Joshua D. Shamblin and Ginger C. Donnelly and Heather L. Esham and Carly B. Wlazlowski and Joshua C Johnson and Anna N Honko and Miriam A. Botto and Judy Y. Yen and Lisa E. Hensley and Arthur J Goff},
  journal={Journal of virology},
  year={2015},
  volume={89 19},
  pages={9875-85}
}
UNLABELLED Marburg virus (MARV) infection is a lethal hemorrhagic fever for which no licensed vaccines or therapeutics are available. Development of appropriate medical countermeasures requires a thorough understanding of the interaction between the host and the pathogen and the resulting disease course. In this study, 15 rhesus macaques were sequentially sacrificed following aerosol exposure to the MARV variant Angola, with longitudinal changes in physiology, immunology, and histopathology… CONTINUE READING
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