Tempo and mode of evolution in an orthologous Can SINE

  title={Tempo and mode of evolution in an orthologous Can SINE},
  author={Sarah M. Zehr and Michael A. Nedbal and John J Flynn},
  journal={Mammalian Genome},
Tempo and mode of nucleotide change were examined in an orthologous carnivoran nuclear repetitive DNA element (Can SINE), and compared with those of the transthyretin intron I (TR-i-I) sequence in which it is embedded, by using a phylogenetic framework. The Can SINE is found in representatives of all living caniform carnivoran families, but no living feliform families. This suggests insertion 40–65 MYA, after the two lineages split, but before the caniform radiation. Despite linkage and a long… CONTINUE READING
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