Template proteogenomics: sequencing whole proteins using an imperfect database.

Abstract

Database search algorithms are the primary workhorses for the identification of tandem mass spectra. However, these methods are limited to the identification of spectra for which peptides are present in the database, preventing the identification of peptides from mutated or alternatively spliced sequences. A variety of methods has been developed to search a… (More)
DOI: 10.1074/mcp.M900504-MCP200

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Cite this paper

@article{Castellana2010TemplatePS, title={Template proteogenomics: sequencing whole proteins using an imperfect database.}, author={Natalie Castellana and Victoria C. Pham and David P Arnott and Jennie R Lill and Vineet Bafna}, journal={Molecular & cellular proteomics : MCP}, year={2010}, volume={9 6}, pages={1260-70} }