Temperature transitions of protein properties in human red blood cells.

@article{Artmann1998TemperatureTO,
  title={Temperature transitions of protein properties in human red blood cells.},
  author={G. M. Artmann and Csaba Kelemen and Dariusz Porst and Georg Bueldt and S Chien},
  journal={Biophysical journal},
  year={1998},
  volume={75 6},
  pages={
          3179-83
        }
}
Human red blood cells (RBC) undergo a sudden change from blocking to passing through 1.3 +/- 0.2-micrometer micropipettes at a transition temperature (Tc) of 36.4 degrees C. For resealed RBC ghosts this transition occurs at 28.3 degrees C (Tg). These findings are attributed to an elastomeric transition of hemoglobin from being gel-like to a fluid and to an elastomeric transition of membrane proteins such as spectrin. Spectrin shows a uniform distribution along the aspirated RBC tongue above Tg… CONTINUE READING
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