Temperature sensitivity of DNA synthesis in mouse testicular germ cells in vitro.

  title={Temperature sensitivity of DNA synthesis in mouse testicular germ cells in vitro.},
  author={Y. Nishimune and S. Aizawa},
  journal={Experimental cell research},
  volume={113 2},
  • Y. Nishimune, S. Aizawa
  • Published 1978
  • Biology, Medicine
  • Experimental cell research
  • The effect of temperature on testicular DNA synthesis in mice was studied in vitro. By using cultures of cryptorchid testis, DNA synthesis of differentiated germ cells, such as intermediate and type B spermatogonia and resting primary spermatocytes, was shown to be temperature-sensitive, while that of undifferentiated type A spermatogonia was not. DNA synthesis of non-germ cells was not temperature-sensitive. This temperature sensitivity of germ cells in DNA synthesis may be one cause of the… CONTINUE READING

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