Temperature-sensitive mutations of the notch locus in Drosophila melanogaster.

  title={Temperature-sensitive mutations of the notch locus in Drosophila melanogaster.},
  author={D L Shellenbarger and J D Mohler},
  volume={81 1},
Temperature-conditional mutations of the Notch locus were characterized in an attempt to understand the organization of a "complex locus" and the control of its function in development. Among 21 newly induced Notch alleles, about one-half are temperature-conditional for some effects, and three are temperature-sensitive for viability. One temperature-sensitive lethal, l(1)Nts1, is functionally non-complementing for all known effects of Notch locus mutations and maps at a single site within the… CONTINUE READING