Temperature-sensitive mutations causing reversible paralysis in Caenorhabditis elegans.

  title={Temperature-sensitive mutations causing reversible paralysis in Caenorhabditis elegans.},
  author={Ryuji Hosono and Shin-ichi Kuno and M Midsukami},
  journal={The Journal of experimental zoology},
  volume={235 3},
A method has been developed for the isolation of temperature-dependent paralytic mutants of the nematode Caenorhabditis elegans, based on a screening procedure using short-time exposure to 30 degrees C. Of ten mutants isolated, eight lose their motilities between 30 degrees C and 33 degrees C without prominent changes in body forms. The other two strains that are mainly described in this report are accompanied by alterations in body forms. One mutation, cn101, is recessive and an allele of cha… CONTINUE READING