Temperature-sensitive influenza A virus clones originated by a cross between A/Aichi/2/68 (H3N2) and B/Yamagata/1/73

Abstract

A genetic cross was performed between influenza viruses B/Yamagata/1/73 and clone 6–10, an A type influenza virus derived from a cross between A/Aichi/2/68 (H3N2) and B/Yamagata. Efficiency of plating of B/Yamagata at 39.5° C was less than 10−3 in MDCK cells, while that of clone 6–10 or A/Aichi was higher than 10−1. Four of the 15 clones selected for HA of… (More)
DOI: 10.1007/BF01314124

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