Temperature-sensitive defect of type 2 poliovirus.

@article{Adler1974TemperaturesensitiveDO,
  title={Temperature-sensitive defect of type 2 poliovirus.},
  author={R. Adler and D. R. Tershak},
  journal={Virology},
  year={1974},
  volume={58 1},
  pages={
          209-18
        }
}
Abstract The temperature sensitivity of type 2 poliovirus, p712 Ch2ab, was investigated. The results show: (1) late, but not early, stages of infection are affected by elevated temperature; (2) extensive breakdown of viral RNA occurs at 40 °; (3) the products of translation at 40 ° are 14,000 molecular weight peptides; (4) formation of these peptides appears to be due to premature termination during translation. 
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SHOWING 1-10 OF 20 REFERENCES
Inhibition of poliovirus RNA synthesis by supraoptimal temperatures.
Degradation of poliovirus polypeptides in vivo.
Degradation of poliovirus RNA in vivo.
Effect of guanidine on the growth of LSc poliovirus.
Polypeptide cleavages in the formation of poliovirus proteins.
  • M. Jacobson, D. Baltimore
  • Chemistry, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 1968
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